Transcriptional regulation of Th2 cell differentiation
نویسندگان
چکیده
منابع مشابه
Transcriptional Regulation of T Helper 17 Cell Differentiation
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متن کاملTranscription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation.
The Th2 locus control region (LCR) has been shown to be important in efficient and coordinated cytokine gene regulation during Th2 cell differentiation. However, the molecular mechanism for this is poorly understood. To study the molecular mechanism of the Th2 LCR, we searched for proteins binding to it. We discovered that transcription factor YY1 bound to the LCR and the entire Th2 cytokine lo...
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ژورنال
عنوان ژورنال: Immunology & Cell Biology
سال: 2010
ISSN: 0818-9641,1440-1711
DOI: 10.1038/icb.2009.114